Chitosan and its derivatives as vehicles for drug delivery
نویسندگان
چکیده
منابع مشابه
Chitosan and Its Derivatives for Drug Delivery Perspective
Biopolymers are promising materials in the delivery of protein drugs due to their compatibility, degradation behavior, and nontoxic nature on administration. On suitable chemical modification, these polymers can provide better materials for drug delivery systems. Nanostructured drug carriers allow the delivery of not only small-molecule drugs but also of nucleic acids and proteins. The use of b...
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Chitosan is a nontoxic, biodegradable, and biocompatible polysaccharide of b(1-4)-linked D-glucosamine and N-acetyl-D-glucosamine. This derivative of natural chitin presents remarkable properties that have paved the way for the introduction of chitosan in the biomedical and pharmaceutical fields. Nevertheless, the properties of chitosan, such as its poor solubility in water or in organic solven...
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Chitosan is a versatile natural polymer. This article reviewed different aspects of Chitosan that’s including preparation and characterization of Chitosan with their applicability in pharmaceutical formulations. Also, the article included different derivatives of Chitosan and their use in different drug delivery system. This review emphasized that research on Chitosan based systems containing v...
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First principles calculations were carried out for investigation the novel 7-hydroxycoumarinyl gallates derivatives in gas and liquid phases using density functional theory (DFT) method. Computational chemistry simulations were carried out to compare calculated quantum chemical parameters for gallates derivatives. All calculations were performed using DMol3 code which is based on DFT. The Doubl...
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The present study deals with the formulation and evaluation of chitosan nanoparticles containing donepezil hydrochloride for the targeted delivery to the brain. Nanoparticles were prepared by ionic gelation method using sodium tripolyphos-phate (TPP) as a cross linking agent followed by sonication. Nanoparticles were obtained in the average size ranging from 116.8 to 227.5 nm. Particle m...
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ژورنال
عنوان ژورنال: Drug Delivery
سال: 2017
ISSN: 1071-7544,1521-0464
DOI: 10.1080/10717544.2017.1399305